本公司成立於2002年，並以『電化學』學理為基礎，從事研究適用於生化、環境、食品、毒物、藥物…等等的檢測技術，並發展能兼顧快速、準確與操作便利的分析工具。有鑑於此，利用網版印刷與射出成型技術發展出具有可拋棄、價格低廉、大量製作、方便可攜帶和多重設計變化等等卓越優點的新一代電極。
NEWS
真的可以冻龄並百毒不侵嗎？ NADH 與 NAD+ 是细胞中的一对氧化还原对，它们作为生物體内 ... more
人們繼太陽能，風能，氫能源之後仍然持續不斷的尋求全新的清潔能源。生物燃料電池是一種利用有機碳來產 ... more
根據美國骨骼健康協會的建議，成年人一天需要1000-1200毫克的鈣質。如果我们不能從飲食中補充 ... more
時至今日，癌症已經成為威脅人類健康的頭號殺手之一。在癌症造成的死亡病例中，癌細胞的轉 ... more
根據 CNN 的報道，南韓已經成為繼中國大陸地區之外 2019&n ... more
時至今日，2019 新型冠狀病毒已經在世界範圍內造成成千上萬的人員感染，並對各國 經濟造成重創。 ... more
真的可以冻龄並百毒不侵嗎？
NADH 與 NAD+ 是细胞中的一对氧化还原对，它们作为生物體内很多氧化還原反應的輔酶参與生命活動，並相互轉化。
2017年3月，哈佛醫學院教授- David Sinclair博士首度在科學月刊發表，NAD+ 具有抗血管衰老的特性且在細胞產生能量及DNA修復過程中上扮演重要角色，提升NAD+濃度同時也減輕了衰老過程中的DNA損傷。换句話說NAD+具有保護細胞抵抗老化的作用。因此，很多研究學者也展開關於提高NAD+濃度對於因細胞老化所導致的糖尿病，帕金斯症，阿茲海默症的研究。
在近期根據2020年4月在Biorxiv的研究報告，更有數據顯示COVID-19對细胞的攻擊會導致NAD降低三倍以上。雖然還在進一步的研究中，但是早期的臨床前數據表明增加细胞质NAD+的水平可以提高细胞對于冠状病毒的抵抗能力。
正因為如此重要，所以關於NADH的檢測也吸引了許多研究學者的關注。目前用於NADH的檢測方法有比色法，光電化學法，酶學測定，高效液相色譜等。在這些方法中，電化學的檢測因其具有高靈敏度，檢測時間短，成本低，甚至可以提供原位即時檢測等優點。因此有望可以開發出可以定量評估老人疾病或某些傳染性疾病的療效檢測方式。
Is it possible to sustain youth and to be impenetrable?
NADH/NAD+ is avital co-enzyme couple that plays a significant role in energy production/consumption within the cells of living organisms.
It was published in Science by Professor David Sinclair(Harvard Medical School,2017) that NAD+ could underlie some effects of aging and propensity to age-related diseases. These include activating the body’s defenses against aging, deleting senescent cells, and reprogramming cells in vivo. Some researchers have found that NADH is beneficial for patients who are suffering from diabetes, Parkinson’s disease, Alzheimer’s disease, and depression.
In April 4 2020,it was reported in Biorxiv that COVID-19 infection strikingly depress NAD levels. Early preclinical data show that nutritional and pharmacological interventions to enhance NAD-based defenses may boost innate immunity.
Due to its importance, NADH detection has received much attention. A variety of analytical methods have been proposed for NADH sensing, including colorimetry, photo-electrochemistry, enzymatic assay, and high- performance liquid chromatography. Among these methods, electrochemical sensors are likely to offer a highly sensitive and in situ analytical approach for the detection of NADH. Due to their rapid response, straightforward operation, and cost effectiveness electrochemical detection method can be applied to explore the predictors of treatment effect in age-related disease or epidemic disease.
Reference：
人們繼太陽能，風能，氫能源之後仍然持續不斷的尋求全新的清潔能源。生物燃料電池是一種利用有機碳來產生電能的新能源。一些科學家已經成功使用尿液來製造第一台“尿尿發電機”，這台發電機就被安裝在西英格兰大学法国校区的廁所裡用來給電燈提供電能。如果某天你決定使用這種新型電池來驅動行動電話甚至一台汽車，到時就不要隨便浪費你的尿尿囉！
As the pursuit for new forms of clean energy continues, with a host of solar, wind and hydropower projects coming online.A new type of battery,bio-fuel cell, is attempted to use organic carbon to produce electricity. Some scienteist used urine to get electricity . It was called ‘Pee Power’. The first Pee Power urinal was installed on the Frenchay Campus at University of West England, in which the lighting within the toilet structure was powered by microbial fuel cells feeding off the urine.If you are want to use this technology to charge mobile phones even a car one day,don’t waste your urine anymore at that time.
Reference
1. Improved Electrical Wiring of Glucose Oxidase Enzyme with an in-Situ Immobilized Mn(1,10-Phenanthroline)2Cl2-Complex/Multiwalled Carbon Nanotube-Modified Electrode Displaying Superior Performance to Os-Complex for High-Current Sensitivity Bioelectrocatalytic and Biofuel Cell Applications
2. One-step preparation of graphitic carbon nitride/Polyaniline/Palladium nanoparticles based nanohybrid composite modified electrode for efficient methanol electro-oxidation
根據美國骨骼健康協會的建議，成年人一天需要1000-1200毫克的鈣質。如果我们不能從飲食中補充足夠的鈣質，身體將從骨骼中强取鈣，這最终將導致骨骼變細變薄。牛奶富含鈣質，所以許多人選擇牛奶作為重要的鈣質來源。Ismail研究指出，在他測試的樣品中大約有一半都有重金屬超標的問題。重金屬超標會引起骨骼損傷、腎衰竭、細胞損傷、骨質疏鬆、肺部和血液的癌症、激素紊亂、腸胃、貧血等問題。牛奶的成分非常複雜。所以如何快速、簡便的檢測成為重要的課題。目前已經有很多使用電化學方式的檢測方法被應用到實際的測試中。
According to American Bone Health Organization, adults need between 1,000 and 1,200 mg of calcium a day. If you don't get enough calcium from your diet, your body will leech what it needs from bone, which ultimately leads to thinning. Milk is rich in calcium, so many people choose it as Calcium supplements. In Ismail’s research , in half of the samples,the level of Pb and Cd was found to exceed the permissible limit (0.02 µg/g and 0.0026 µg/g) set by International Dairy Federation. The toxic impacts of heavy metals on human health include skeletal damages, renal failure, cell damages, osteoporosis, cancer of lungs and blood, hormonal disturbances, gastrointestinal problems and anemia. Milk is chemically very complex, with many different ingredients. So detectiong the level of heavy metal in milk is turned into an important task. Up to now many achievements in electrochemisty field have been reported an used for actual test,which is easy to use and cheaply.
Reference
1.Simultaneous determination of Cd(II) and Pb(II) ions in honey and milk samples using a single-walled carbon nanohorns modified screen-printed electrochemical sensor
2.Sonochemical synthesis of gum guar biopolymer stabilized copper oxide on exfoliated graphite: Application for enhanced electrochemical detection of H2O2 in milk and pharmaceutical samples
時至今日，癌症已經成為威脅人類健康的頭號殺手之一。在癌症造成的死亡病例中，癌細胞的轉移占了絕大部分，而癌細胞的轉移又與從原發癌脫落的循環腫瘤細胞（CTCs）有著密切的關係。所以如果可以檢測血液中低濃度的循環腫瘤細胞對于及時發現癌症轉移以及評估癌症治療方案有著重大的幫助。有研究學者報道，他們在5mL的健康血液中加入十個小細胞肺癌細胞，通過他們設計的微流體裝置，可以檢測出93%的目標物。如今在循环肿瘤细胞的分离和检测中，諸如比色法，電化學法，螢光發光影像法都被廣泛時候用。在這些技術中，電化學感測技術由於其獨特的優點（低成本，高靈敏度，操作簡便）而倍加矚目。
To date, cancer is one of the leading causes of death in human beings. One of the major causes of cancer-related deaths is cancer metastasis, which is closely correlated with circulating tumor cells(CTCs). Detecting CTCs at low concentrations is beneficial for real time monitoring of cancer metastasis and therapies. Some researchers reported they used 5-milliliter samples of healthy blood with 10 small-cell-lung cancer cells and then ran the blood through their device. They were able to recover 93 percent of the cancer cells using the microfluidic device. Many new techniques, including colorimetric, electrochemical and fluorescent imaging, have been effectively exploited to isolate and enumerate CTCs. Among these techniques, the electrochemical sensing methods are very attractive by virtue of their unique features, including low cost, high sensitivity and facile operation.
Reference
1. Diagnostic Detection of Human Lung Cancer-Associated Antigen Using a Gold Nanoparticle-Based Electrochemical Immunosensor
2. Highly sensitive biosensor based on graphene–poly (3-aminobenzoic acid) modified electrodes and porous-hollowed-silver-gold nanoparticle labelling for prostate cancer detection
R&D Technology
電化學分析儀適用於實驗室的生化、環境、毒物、食品、藥物等檢測之化學感應器的研發；具自由編寫程序與校正曲線，並執行臨床獨立離線使用功能。
電化學偵測器為高效能液相層析提供一個靈敏、可靠及簡單的電化學偵測平台，它多樣的偵測模式適於分析廣泛的化合物。
網版印刷電極利用網版印刷技術發展出具有可拋棄、價格低廉、大量製作、方便可攜帶和多重設計變化等等的卓越優點的新一代電極。
電極客製服務
Ag100 銀電極
| 名稱 | 編號 | 特性描述 | View | Download |
|---|---|---|---|---|
| 銀電極
(Silver-E) |
Ag100 | 5 mm / 0.196cm2 | ||
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應用：鹵素…等。 結合方法：電化學分析儀、HPLC、FIA…等。 | |||
NCSE 奈米銅網版印刷電極
AUSE100 金電極
AUTE100 金電極
AUTE200 金電極
我們提供更多更適合研究與量產的工具平台，讓研究成果得以順利地往產業量產的方向前進，發展出獨特的化學感測器。
